Mukono District, with a total area of 2,986.47 Sq Km, lies in the Central region of Uganda, sharing borders with the Buikwe District in the East, Kayunga along River Sezibwa in the North, Luwero in the North West, Kampala and Wakiso in South West, Tanzania - Lake Victoria in the South with the Islands of Buvuma District.

The District Headquarters is in Mukono municipality central division, situated along Kampala-Jinja road (21Kms East of Kampala City).

Mukono central division serves as an administrative and commercial centre.  Other urban centers include Katosi, Kasawo and Nakifuma town boards.

Sezibwa Falls is a Buganda Cultural Heritage Site that is found in Mukono District. It is situated only 20 miles on the Kampala – Jinja Highway and about 1.5km off. The Sezibwa Falls preserves an ancient African culture and has for ages been a site of traditional cultural rituals for traditional believers.